| Segunda Division | 1 | 2009-08-30 | HOME | FC Salamanca | 0-1 |
| Segunda Division | 2 | 2009-09-05 | AWAY | Levante UD | 1-1 |
| Segunda Division | 3 | 2009-09-12 | HOME | Cordoba | 0-0 |
| Segunda Division | 4 | 2009-09-20 | AWAY | Hercules Alicante CF | 1-0 |
| Segunda Division | 5 | 2009-09-26 | HOME | Recreativo de Huelva | 1-0 |
| Segunda Division | 6 | 2009-10-04 | AWAY | Albacete Palomie | 0-1 |
| Segunda Division | 7 | 2009-10-11 | HOME | FC Cartagena | 1-3 |
| Segunda Division | 8 | 2009-10-17 | AWAY | Rayo Vallecano | 2-2 |
| Segunda Division | 9 | 2009-10-25 | HOME | Real Union Irun | 2-1 |
| Segunda Division | 10 | 2009-10-31 | AWAY | CD Castellon | 4-1 |
| Segunda Division | 11 | 2009-11-08 | HOME | Real Betis Sevilla | 2-2 |
| Segunda Division | 12 | 2009-11-14 | AWAY | Villarreal CF B | 2-0 |
| Segunda Division | 13 | 2009-11-21 | AWAY | Girona FC | 4-0 |
| Segunda Division | 14 | 2009-11-28 | HOME | Celta Vigo | 3-1 |
| Segunda Division | 15 | 2009-12-05 | AWAY | FC Elche | 1-1 |
| Segunda Division | 16 | 2009-12-13 | HOME | Las Palmas | 0-0 |
| Segunda Division | 17 | 2009-12-20 | AWAY | Real Murcia | 2-2 |
| Segunda Division | 18 | 2010-01-03 | HOME | Club Gimnastic de Tarragona | 0-1 |
| Segunda Division | 19 | 2010-01-09 | AWAY | Real Sociedad | 4-1 |
| Segunda Division | 20 | 2010-01-16 | HOME | SD Huesca | 0-0 |
| Segunda Division | 21 | 2010-01-23 | AWAY | Numancia CD | 1-3 |
| Segunda Division | 22 | 2010-01-31 | AWAY | FC Salamanca | 1-1 |
| Segunda Division | 23 | 2010-02-07 | HOME | Levante UD | 2-4 |
| Segunda Division | 24 | 2010-02-12 | AWAY | Cordoba | 1-0 |
| Segunda Division | 25 | 2010-02-21 | HOME | Hercules Alicante CF | 2-2 |
| Segunda Division | 26 | 2010-02-27 | AWAY | Recreativo de Huelva | 2-1 |
| Segunda Division | 27 | 2010-03-07 | HOME | Albacete Palomie | 4-3 |
| Segunda Division | 28 | 2010-03-12 | AWAY | FC Cartagena | 4-1 |
| Segunda Division | 29 | 2010-03-21 | HOME | Rayo Vallecano | 1-1 |
| Segunda Division | 30 | 2010-03-26 | AWAY | Real Union Irun | 0-0 |
| Segunda Division | 31 | 2010-04-04 | HOME | CD Castellon | 1-0 |
| Segunda Division | 32 | 2010-04-10 | AWAY | Real Betis Sevilla | 4-0 |
| Segunda Division | 33 | 2010-04-18 | HOME | Villarreal CF B | 0-0 |
| Segunda Division | 34 | 2010-04-25 | HOME | Girona FC | 2-0 |
| Segunda Division | 35 | 2010-05-01 | AWAY | Celta Vigo | 2-1 |
| Segunda Division | 36 | 2010-05-09 | HOME | FC Elche | 2-1 |
| Segunda Division | 37 | 2010-05-15 | AWAY | Las Palmas | 1-1 |
| Segunda Division | 38 | 2010-05-23 | HOME | Real Murcia | 1-0 |
| Segunda Division | 39 | 2010-05-30 | AWAY | Club Gimnastic de Tarragona | 0-2 |
| Segunda Division | 40 | 2010-06-05 | HOME | Real Sociedad | 1-3 |
| Segunda Division | 41 | 2010-06-13 | AWAY | SD Huesca | 2-1 |
| Segunda Division | 42 | 2010-06-19 | HOME | Numancia CD | 4-2 |
