| Bundesliga | 1 | 2015-08-15 | HOME | Hannover 96 | 2-2 |
| Bundesliga | 2 | 2015-08-22 | AWAY | FC Schalke 04 | 1-1 |
| Bundesliga | 3 | 2015-08-29 | HOME | TSG Hoffenheim | 0-0 |
| Bundesliga | 4 | 2015-09-12 | AWAY | Bayer Leverkusen | 0-1 |
| Bundesliga | 5 | 2015-09-19 | HOME | FC Bayern Munchen | 0-3 |
| Bundesliga | 6 | 2015-09-22 | HOME | SV Werder Bremen | 2-1 |
| Bundesliga | 7 | 2015-09-27 | AWAY | Borussia Dortmund | 2-2 |
| Bundesliga | 8 | 2015-10-02 | HOME | FSV Mainz | 2-3 |
| Bundesliga | 9 | 2015-10-17 | AWAY | FC Augsburg | 0-2 |
| Bundesliga | 10 | 2015-10-24 | HOME | VfL Wolfsburg | 0-1 |
| Bundesliga | 11 | 2015-11-01 | AWAY | VfB Stuttgart | 2-0 |
| Bundesliga | 12 | 2015-11-07 | HOME | Hamburger SV | 1-1 |
| Bundesliga | 13 | 2015-11-22 | AWAY | FC Ingolstadt 04 | 3-1 |
| Bundesliga | 14 | 2015-11-27 | HOME | FC Koln | 0-0 |
| Bundesliga | 15 | 2015-12-06 | AWAY | Eintracht Frankfurt | 0-1 |
| Bundesliga | 16 | 2015-12-12 | HOME | Hertha BSC Berlin | 0-4 |
| Bundesliga | 17 | 2015-12-20 | AWAY | Borussia Monchengladbach | 3-2 |
| Bundesliga | 18 | 2016-01-23 | AWAY | Hannover 96 | 1-2 |
| Bundesliga | 19 | 2016-01-30 | HOME | FC Schalke 04 | 0-2 |
| Bundesliga | 20 | 2016-02-07 | AWAY | TSG Hoffenheim | 0-2 |
| Bundesliga | 21 | 2016-02-13 | HOME | Bayer Leverkusen | 1-2 |
| Bundesliga | 22 | 2016-02-20 | AWAY | FC Bayern Munchen | 3-1 |
| Bundesliga | 23 | 2016-02-27 | AWAY | SV Werder Bremen | 2-2 |
| Bundesliga | 24 | 2016-03-02 | HOME | Borussia Dortmund | 0-2 |
| Bundesliga | 25 | 2016-03-06 | AWAY | FSV Mainz | 0-0 |
| Bundesliga | 26 | 2016-03-12 | HOME | FC Augsburg | |
| Bundesliga | 27 | 2016-03-19 | AWAY | VfL Wolfsburg | |
| Bundesliga | 28 | 2016-04-02 | HOME | VfB Stuttgart | |
| Bundesliga | 29 | 2016-04-09 | AWAY | Hamburger SV | |
| Bundesliga | 30 | 2016-04-16 | HOME | FC Ingolstadt 04 | |
| Bundesliga | 31 | 2016-04-23 | AWAY | FC Koln | |
| Bundesliga | 32 | 2016-04-29 | HOME | Eintracht Frankfurt | |
| Bundesliga | 33 | 2016-05-07 | AWAY | Hertha BSC Berlin | |
| Bundesliga | 34 | 2016-05-14 | HOME | Borussia Monchengladbach |
