| Ligue 2 | 1 | 2010-08-06 | HOME | AC Le Havre | 1-0 |
| Ligue 2 | 2 | 2010-08-13 | AWAY | CS Sedan-Ardennes | 1-0 |
| Ligue 2 | 3 | 2010-08-17 | HOME | SCO Angers | 0-2 |
| Ligue 2 | 4 | 2010-08-20 | AWAY | Nimes Olympique | 1-0 |
| Ligue 2 | 5 | 2010-08-30 | HOME | UC Le Mans | 0-1 |
| Ligue 2 | 6 | 2010-09-10 | AWAY | FC Istres | 0-1 |
| Ligue 2 | 7 | 2010-09-17 | HOME | ES Troyes AC | 0-2 |
| Ligue 2 | 8 | 2010-09-24 | AWAY | FC Nantes | 2-1 |
| Ligue 2 | 9 | 2010-10-01 | HOME | Vannes OC | 1-2 |
| Ligue 2 | 10 | 2010-10-15 | AWAY | Stade Laval | 3-0 |
| Ligue 2 | 11 | 2010-10-19 | HOME | FC Metz | 1-0 |
| Ligue 2 | 12 | 2010-10-22 | AWAY | Stade Reims | 4-1 |
| Ligue 2 | 13 | 2010-10-29 | HOME | AC Ajaccio | 1-1 |
| Ligue 2 | 14 | 2010-11-05 | AWAY | Chateauroux | 4-3 |
| Ligue 2 | 15 | 2010-11-12 | HOME | Tours FC | 2-2 |
| Ligue 2 | 16 | 2010-11-26 | AWAY | Evian Thonon Gaillar | 2-0 |
| Ligue 2 | 17 | 2010-12-03 | AWAY | US Boulogne CO | 2-0 |
| Ligue 2 | 18 | 2010-12-17 | HOME | Dijon FC | 3-1 |
| Ligue 2 | 19 | 2010-12-21 | AWAY | Clermont Foot | 2-2 |
| Ligue 2 | 20 | 2011-01-15 | HOME | CS Sedan-Ardennes | 1-1 |
| Ligue 2 | 21 | 2011-01-29 | AWAY | SCO Angers | 2-2 |
| Ligue 2 | 22 | 2011-02-05 | HOME | Nimes Olympique | 1-0 |
| Ligue 2 | 23 | 2011-02-12 | AWAY | UC Le Mans | 1-0 |
| Ligue 2 | 24 | 2011-02-18 | HOME | FC Istres | 0-2 |
| Ligue 2 | 25 | 2011-02-25 | AWAY | ES Troyes AC | 2-0 |
| Ligue 2 | 26 | 2011-03-04 | HOME | FC Nantes | 2-0 |
| Ligue 2 | 27 | 2011-03-11 | AWAY | Vannes OC | 1-1 |
| Ligue 2 | 28 | 2011-03-18 | HOME | Stade Laval | 1-2 |
| Ligue 2 | 29 | 2011-04-01 | AWAY | FC Metz | 0-1 |
| Ligue 2 | 30 | 2011-04-08 | HOME | Stade Reims | 1-1 |
| Ligue 2 | 31 | 2011-04-15 | AWAY | AC Ajaccio | 1-0 |
| Ligue 2 | 32 | 2011-04-22 | HOME | Chateauroux | 1-1 |
| Ligue 2 | 33 | 2011-04-29 | AWAY | Tours FC | 2-2 |
| Ligue 2 | 34 | 2011-05-06 | HOME | Evian Thonon Gaillar | 1-1 |
| Ligue 2 | 35 | 2011-05-10 | HOME | US Boulogne CO | 2-2 |
| Ligue 2 | 36 | 2011-05-16 | AWAY | Dijon FC | 2-1 |
| Ligue 2 | 37 | 2011-05-20 | HOME | Clermont Foot | 2-2 |
| Ligue 2 | 38 | 2011-05-27 | AWAY | AC Le Havre | 5-0 |
