| Premier League | 1 | 2015-08-08 | AWAY | Leicester City | 4-2 |
| Premier League | 2 | 2015-08-15 | HOME | Norwich City | 1-3 |
| Premier League | 3 | 2015-08-22 | HOME | Swansea City | 1-1 |
| Premier League | 4 | 2015-08-29 | AWAY | Aston Villa | 2-2 |
| Premier League | 5 | 2015-09-13 | HOME | Tottenham Hotspur | 0-1 |
| Premier League | 6 | 2015-09-19 | AWAY | AFC Bournemouth | 2-0 |
| Premier League | 7 | 2015-09-26 | AWAY | Manchester United | 3-0 |
| Premier League | 8 | 2015-10-03 | HOME | West Ham United | 2-2 |
| Premier League | 9 | 2015-10-17 | AWAY | West Bromwich Albion | 1-0 |
| Premier League | 10 | 2015-10-25 | HOME | Newcastle United | 3-0 |
| Premier League | 11 | 2015-11-01 | AWAY | Everton | 6-2 |
| Premier League | 12 | 2015-11-07 | HOME | Southampton | 0-1 |
| Premier League | 13 | 2015-11-23 | AWAY | Crystal Palace | 0-1 |
| Premier League | 14 | 2015-11-28 | HOME | Stoke City | 2-0 |
| Premier League | 15 | 2015-12-05 | AWAY | Arsenal | 3-1 |
| Premier League | 16 | 2015-12-12 | HOME | Watford | 0-1 |
| Premier League | 17 | 2015-12-19 | AWAY | Chelsea | 3-1 |
| Premier League | 18 | 2015-12-26 | AWAY | Manchester City | 4-1 |
| Premier League | 19 | 2015-12-30 | HOME | Liverpool | 0-1 |
| Premier League | 20 | 2016-01-02 | HOME | Aston Villa | 3-1 |
| Premier League | 21 | 2016-01-13 | AWAY | Swansea City | 2-4 |
| Premier League | 22 | 2016-01-16 | AWAY | Tottenham Hotspur | 4-1 |
| Premier League | 23 | 2016-01-23 | HOME | AFC Bournemouth | 1-1 |
| Premier League | 24 | 2016-02-02 | HOME | Manchester City | 0-1 |
| Premier League | 25 | 2016-02-06 | AWAY | Liverpool | 2-2 |
| Premier League | 26 | 2016-02-13 | HOME | Manchester United | 2-1 |
| Premier League | 27 | 2016-02-27 | AWAY | West Ham United | 1-0 |
| Premier League | 28 | 2016-03-01 | HOME | Crystal Palace | 2-2 |
| Premier League | 29 | 2016-03-05 | AWAY | Southampton | 1-1 |
| Premier League | 30 | 2016-03-12 | HOME | Everton | |
| Premier League | 31 | 2016-03-20 | AWAY | Newcastle United | |
| Premier League | 32 | 2016-04-02 | HOME | West Bromwich Albion | |
| Premier League | 33 | 2016-04-10 | HOME | Leicester City | |
| Premier League | 34 | 2016-04-16 | AWAY | Norwich City | |
| Premier League | 35 | 2016-04-24 | HOME | Arsenal | |
| Premier League | 36 | 2016-04-30 | AWAY | Stoke City | |
| Premier League | 37 | 2016-05-07 | HOME | Chelsea | |
| Premier League | 38 | 2016-05-15 | AWAY | Watford |
