| Jupiler League | 1 | 2007-08-04 | HOME | Germinal Beerschot | 1-2 |
| Jupiler League | 2 | 2007-08-11 | AWAY | KSV Roeselare | 3-1 |
| Jupiler League | 3 | 2007-08-18 | HOME | RSC Anderlecht | 2-2 |
| Jupiler League | 4 | 2007-08-25 | AWAY | Cercle Brugge KSV | 3-0 |
| Jupiler League | 5 | 2007-09-01 | HOME | Sint-Truidense VV | 1-0 |
| Jupiler League | 6 | 2007-09-15 | AWAY | KVC Westerlo | 0-0 |
| Jupiler League | 7 | 2007-09-22 | HOME | RAEC Mons | 0-3 |
| Jupiler League | 8 | 2007-09-30 | AWAY | KV Mechelen | 2-2 |
| Jupiler League | 9 | 2007-10-06 | HOME | Sporting Lokeren | 0-1 |
| Jupiler League | 10 | 2007-10-20 | AWAY | Club Brugge KV | 2-0 |
| Jupiler League | 11 | 2007-10-27 | HOME | Royal Excelsior Mouscron | 0-3 |
| Jupiler League | 12 | 2007-11-03 | AWAY | Royal Charleroi SC | 1-0 |
| Jupiler League | 13 | 2007-11-10 | AWAY | FC Brussels | 4-1 |
| Jupiler League | 14 | 2007-12-01 | HOME | KRC Genk | 2-0 |
| Jupiler League | 15 | 2007-12-08 | AWAY | SV Zulte-Waregem | 1-2 |
| Jupiler League | 16 | 2007-12-15 | HOME | Standard Liege | 0-0 |
| Jupiler League | 17 | 2007-12-22 | AWAY | KAA Gent | 2-4 |
| Jupiler League | 18 | 2008-01-19 | AWAY | Germinal Beerschot | 1-0 |
| Jupiler League | 19 | 2008-01-26 | HOME | KSV Roeselare | 2-1 |
| Jupiler League | 20 | 2008-02-02 | AWAY | RSC Anderlecht | 1-0 |
| Jupiler League | 21 | 2008-02-09 | HOME | Cercle Brugge KSV | 2-4 |
| Jupiler League | 22 | 2008-02-16 | AWAY | Sint-Truidense VV | 1-2 |
| Jupiler League | 23 | 2008-02-23 | HOME | KVC Westerlo | 2-0 |
| Jupiler League | 24 | 2008-03-01 | AWAY | RAEC Mons | 2-2 |
| Jupiler League | 25 | 2008-03-08 | HOME | KV Mechelen | 0-3 |
| Jupiler League | 26 | 2008-03-15 | AWAY | Sporting Lokeren | 1-0 |
| Jupiler League | 27 | 2008-03-22 | HOME | Club Brugge KV | 1-0 |
| Jupiler League | 28 | 2008-03-29 | AWAY | Royal Excelsior Mouscron | 2-1 |
| Jupiler League | 29 | 2008-04-05 | HOME | Royal Charleroi SC | 2-4 |
| Jupiler League | 30 | 2008-04-12 | HOME | FC Brussels | 1-1 |
| Jupiler League | 31 | 2008-04-20 | AWAY | KRC Genk | 2-0 |
| Jupiler League | 32 | 2008-04-26 | HOME | SV Zulte-Waregem | 2-1 |
| Jupiler League | 33 | 2008-05-03 | AWAY | Standard Liege | 3-0 |
| Jupiler League | 34 | 2008-05-10 | HOME | KAA Gent | 0-3 |
