| 2018-11-24 | Udinese Calcio | 1-0 | AS Roma |
| 2018-11-24 | FC Juventus | 2-0 | Spal |
| 2018-11-24 | FC Internazionale | 3-0 | Frosinone Calcio |
| 2018-11-25 | Parma AC | 2-1 | Sassuolo Calcio |
| 2018-11-25 | Bologna FC | 0-0 | AC Fiorentina |
| 2018-11-25 | Empoli FC | 3-2 | Atalanta BC |
| 2018-11-25 | SSC Napoli | 0-0 | AC Chievo Verona |
| 2018-11-25 | SS Lazio | 1-1 | AC Milan |
| 2018-11-25 | Genoa CFC | 1-1 | UC Sampdoria |
| 2018-11-26 | US Cagliari | 0-0 | Torino |
| Home | 5 |
| Draw | 5 |
| Away | 0 |
| Under | 7 |
| Over | 3 |
| Pos | Team | M. | W | D | L | GF | GA | Pts |
|---|---|---|---|---|---|---|---|---|
| 1 | FC Juventus | 13 | 12 | 1 | 0 | 28 | 8 | 37 |
| 2 | SSC Napoli | 13 | 9 | 2 | 2 | 26 | 13 | 29 |
| 3 | FC Internazionale | 13 | 9 | 1 | 3 | 25 | 10 | 28 |
| 4 | SS Lazio | 13 | 7 | 2 | 4 | 19 | 15 | 23 |
| 5 | AC Milan | 13 | 6 | 4 | 3 | 22 | 17 | 22 |
| 6 | Parma AC | 13 | 6 | 2 | 5 | 14 | 16 | 20 |
| 7 | AS Roma | 13 | 5 | 4 | 4 | 22 | 16 | 19 |
| 8 | Sassuolo Calcio | 13 | 5 | 4 | 4 | 21 | 19 | 19 |
| 9 | Atalanta BC | 13 | 5 | 3 | 5 | 25 | 17 | 18 |
| 10 | AC Fiorentina | 13 | 4 | 6 | 3 | 18 | 10 | 18 |
| 11 | Torino | 13 | 4 | 6 | 3 | 17 | 15 | 18 |
| 12 | UC Sampdoria | 13 | 4 | 4 | 5 | 17 | 16 | 16 |
| 13 | US Cagliari | 13 | 3 | 6 | 4 | 12 | 16 | 15 |
| 14 | Genoa CFC | 13 | 4 | 3 | 6 | 18 | 27 | 15 |
| 15 | Spal | 13 | 4 | 1 | 8 | 11 | 21 | 13 |
| 16 | Udinese Calcio | 13 | 3 | 3 | 7 | 12 | 18 | 12 |
| 17 | Empoli FC | 13 | 3 | 3 | 7 | 15 | 23 | 12 |
| 18 | Bologna FC | 13 | 2 | 5 | 6 | 11 | 18 | 11 |
| 19 | Frosinone Calcio | 13 | 1 | 4 | 8 | 10 | 28 | 7 |
| 20 | AC Chievo Verona | 13 | 0 | 4 | 9 | 10 | 30 | 4 |
