| 2018-11-02 | SSC Napoli | 5-1 | Empoli FC |
| 2018-11-03 | FC Internazionale | 5-0 | Genoa CFC |
| 2018-11-03 | AC Fiorentina | 1-1 | AS Roma |
| 2018-11-03 | FC Juventus | 3-1 | US Cagliari |
| 2018-11-04 | SS Lazio | 4-1 | Spal |
| 2018-11-04 | AC Chievo Verona | 0-2 | Sassuolo Calcio |
| 2018-11-04 | Parma AC | 0-0 | Frosinone Calcio |
| 2018-11-04 | UC Sampdoria | 1-4 | Torino |
| 2018-11-04 | Bologna FC | 1-2 | Atalanta BC |
| 2018-11-04 | Udinese Calcio | 0-1 | AC Milan |
| Home | 4 |
| Draw | 2 |
| Away | 4 |
| Under | 4 |
| Over | 6 |
| Pos | Team | M. | W | D | L | GF | GA | Pts |
|---|---|---|---|---|---|---|---|---|
| 1 | FC Juventus | 11 | 10 | 1 | 0 | 24 | 8 | 31 |
| 2 | FC Internazionale | 11 | 8 | 1 | 2 | 21 | 6 | 25 |
| 3 | SSC Napoli | 11 | 8 | 1 | 2 | 24 | 12 | 25 |
| 4 | AC Milan | 11 | 6 | 3 | 2 | 21 | 14 | 21 |
| 5 | SS Lazio | 11 | 7 | 0 | 4 | 17 | 13 | 21 |
| 6 | Sassuolo Calcio | 11 | 5 | 3 | 3 | 19 | 16 | 18 |
| 7 | Torino | 11 | 4 | 5 | 2 | 16 | 13 | 17 |
| 8 | AC Fiorentina | 11 | 4 | 4 | 3 | 17 | 9 | 16 |
| 9 | AS Roma | 11 | 4 | 4 | 3 | 18 | 14 | 16 |
| 10 | Atalanta BC | 11 | 4 | 3 | 4 | 19 | 13 | 15 |
| 11 | UC Sampdoria | 11 | 4 | 3 | 4 | 15 | 11 | 15 |
| 12 | Parma AC | 11 | 4 | 2 | 5 | 10 | 14 | 14 |
| 13 | Genoa CFC | 11 | 4 | 2 | 5 | 16 | 24 | 14 |
| 14 | US Cagliari | 11 | 3 | 4 | 4 | 10 | 14 | 13 |
| 15 | Spal | 11 | 4 | 0 | 7 | 9 | 17 | 12 |
| 16 | Udinese Calcio | 11 | 2 | 3 | 6 | 10 | 16 | 9 |
| 17 | Bologna FC | 11 | 2 | 3 | 6 | 9 | 16 | 9 |
| 18 | Empoli FC | 11 | 1 | 3 | 7 | 10 | 20 | 6 |
| 19 | Frosinone Calcio | 11 | 1 | 3 | 7 | 9 | 24 | 6 |
| 20 | AC Chievo Verona | 11 | 0 | 2 | 9 | 8 | 28 | 2 |
