| 2018-10-27 | Atalanta BC | 3-0 | Parma AC |
| 2018-10-27 | Empoli FC | 1-2 | FC Juventus |
| 2018-10-27 | Torino | 1-1 | AC Fiorentina |
| 2018-10-28 | Sassuolo Calcio | 2-2 | Bologna FC |
| 2018-10-28 | US Cagliari | 2-1 | AC Chievo Verona |
| 2018-10-28 | Genoa CFC | 2-2 | Udinese Calcio |
| 2018-10-28 | Spal | 0-3 | Frosinone Calcio |
| 2018-10-28 | AC Milan | 3-2 | UC Sampdoria |
| 2018-10-28 | SSC Napoli | 1-1 | AS Roma |
| 2018-10-29 | SS Lazio | 0-3 | FC Internazionale |
| Home | 3 |
| Draw | 4 |
| Away | 3 |
| Under | 2 |
| Over | 8 |
| Pos | Team | M. | W | D | L | GF | GA | Pts |
|---|---|---|---|---|---|---|---|---|
| 1 | FC Juventus | 10 | 9 | 1 | 0 | 21 | 7 | 28 |
| 2 | FC Internazionale | 10 | 7 | 1 | 2 | 16 | 6 | 22 |
| 3 | SSC Napoli | 10 | 7 | 1 | 2 | 19 | 11 | 22 |
| 4 | AC Milan | 10 | 5 | 3 | 2 | 20 | 14 | 18 |
| 5 | SS Lazio | 10 | 6 | 0 | 4 | 13 | 12 | 18 |
| 6 | AC Fiorentina | 10 | 4 | 3 | 3 | 16 | 8 | 15 |
| 7 | UC Sampdoria | 10 | 4 | 3 | 3 | 14 | 7 | 15 |
| 8 | AS Roma | 10 | 4 | 3 | 3 | 17 | 13 | 15 |
| 9 | Sassuolo Calcio | 10 | 4 | 3 | 3 | 17 | 16 | 15 |
| 10 | Torino | 10 | 3 | 5 | 2 | 12 | 12 | 14 |
| 11 | Genoa CFC | 10 | 4 | 2 | 4 | 16 | 19 | 14 |
| 12 | US Cagliari | 10 | 3 | 4 | 3 | 9 | 11 | 13 |
| 13 | Parma AC | 10 | 4 | 1 | 5 | 10 | 14 | 13 |
| 14 | Atalanta BC | 10 | 3 | 3 | 4 | 17 | 12 | 12 |
| 15 | Spal | 10 | 4 | 0 | 6 | 8 | 13 | 12 |
| 16 | Udinese Calcio | 10 | 2 | 3 | 5 | 10 | 15 | 9 |
| 17 | Bologna FC | 10 | 2 | 3 | 5 | 8 | 14 | 9 |
| 18 | Empoli FC | 10 | 1 | 3 | 6 | 9 | 15 | 6 |
| 19 | Frosinone Calcio | 10 | 1 | 2 | 7 | 9 | 24 | 5 |
| 20 | AC Chievo Verona | 10 | 0 | 2 | 8 | 8 | 26 | 2 |
